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UPGRADE Kick-Off Meeting, Milan

The UPGRADE (Unlocking Precision Gene Therapy)  kick-off meeting (KOM) was held on 1 March, 2019 at the SR-TIGET facilities in Milan. Around 35 participants representing 6 European Countries attended the meeting. During the meeting all issues related to the implementation, management, dissemination, finance and technicalities of the UPGRADE project were presented and discussed. The participants mostly… Continue reading UPGRADE Kick-Off Meeting, Milan

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Press release: Launch of the UPGRADE project

Fondazione Telethon announces the launch of the UPGRADE project, funded by the European Union with 15 million euros, aiming at developing more precise and effective gene therapies approaches. Coordinated by Luigi Naldini, director of the San Raffaele-Telethon Institute for Gene Therapy (SR-TIGET) in Milan, this 5-year project will involve several of the most important scientific groups of… Continue reading Press release: Launch of the UPGRADE project

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UPGRADE Institutions

UPGRADE gathers together leading European and an American scientist in field of precision gene therapy. Together, this consortium has the unique expertise to create innovative tools to expand efficacy and safety of gene targeting technologies, convert viral-vectors to specifically target cell types and decreased immunogenicity of novel AMP. The participants of UPGRADE have been selected from across… Continue reading UPGRADE Institutions

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Gene therapies

In recent years, gene therapy has shown a remarkable potential to offer definitive treatments for otherwise incurable diseases. By the end of 2017, seven gene therapy products have reached the market and many more are entering clinical testing. These recent successes are largely attributable to incremental step-wise improvements in the efficiency and safety of delivery tools, the most… Continue reading Gene therapies

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Gene editing

Targeted engineering of the human genome opens up an enormous number of new research opportunities and therapeutic possibilities. We are just at the beginning of the “age of genome editing” and we have already witnessed the amazing potential of these technologies to transform research, making possible to design and execute an unprecedented arrays of experimental studies, and attract… Continue reading Gene editing