Work Packages WP TITLE 1 Novel strategies to increase precision and efficacy of gene and epigenetic editing 2 Retargeting gene/vector integration 3 Genome-wide off-target profiling of gene-editing reagents 4 Viral and non-viral mediated delivery of genes and genome engineering components 5 Increase immune evasion of genome engineering components 6 Advanced genetic engineering of hematopoiesis 7 Novel strategies to target skeletal and cardiac muscle wasting in aging and disease conditions 8 Retinal degeneration 9 Expanding the breadth of liver-directed gene therapy to include larger patient populations 10 Management and Scientific coordination 11 Communication, dissemination, stakeholders engagement and exploitation 12 Ethics requirements
