UPGRADE will offer radical new solutions to the hurdles that currently limit efficacy and safety of conventional and emerging gene therapy approaches, ultimately delivering versatile prototypes of advanced medicinal products (AMP) towards a selected panel of diseases.
What is UPGRADE? Which countries are involved in UPGRADE? Which are UPGRADE goals?
UPGRADE ambition is to develop a portfolio of new disruptive gene therapy technologies, to characterize in depth their safety profile and cellular response, to combine these improvements with advanced gene delivery approaches, and to assess safety and efficacy of the corresponding AMP in disease models paradigmatic for unmet medical need and potential long-term cure.
UPGRADE provides a unique blend of expertise in different areas, including technology development, tissue regeneration, disease mechanisms, preclinical and clinical AMP development.
